Improved sensitivity and resolution of state-of-the-art LC–MS systems make it necessary to carefully design sample preparation and analysis workflows. Issues such as solvent and additive choice, handling and storage, as well as equipment cleaning and column selection must be treated sensibly in order to get the best out of any system. Any impurity or contamination will negatively affect sensitivity and hence increase the limit of detection. Next to the solvents and reagents used, the HPLC column and tubing or consumables such as filters and container materials can also be the source of contaminants.
In this webcast, the origins and problems in LC–MS arising from impurities and contaminations will be described in detail and tips and tricks will be provided in order to enable or maintain high quality and high sensitivity LC-MS analyses.
Key points of the webcast are:
Key Learning Objectives:
Who Should Attend:
Technicians and scientists working with HPLC and MS instrumentation.
For questions please contact Kristen Moore: email@example.com