HPLC for Pharmaceutical Analyses: Succeed with Sample Filtration and Optimized Water Quality
This webcast was recorded on April 09, 2014.

The entire pharmaceutical development workflow, from discovery to manufacturing and QC, relies heavily on HPLC and LC-MS analysis. Many chromatography challenges, such as poor peak resolution, poor run reproducibility, or short column life, can be traced back to improper sample preparation or mobile phase preparation. In this seminar, Vivek Joshi, PhD, of EMD Millipore reviews filtration as a sample prep technique and factors to consider while selecting appropriate filtration formats based on the stage within the pharmaceutical workflow. You will learn how to select appropriate high-throughput filtration systems commonly used in drug discovery, as well as considerations for lower-throughput approaches for manufacturing and QC operations. Dr. Joshi will also discuss tips and tricks for reducing extractables and nonspecific analyte binding. Then, Maricar Tarun-Dube, PhD, will explain the importance of ultrapure water quality in HPLC and LC–MS, demonstrating how contamination in reagent water can compromise analyses. Specifically, she will describe the challenges posed by particulates, bacteria, and organic molecules present in the mobile phase as well as strategies for overcoming these challenges.


Vivek Joshi, PhD

Principal Research Scientist
EMD Millipore

Maricar Tarun-Dube, PhD
Global Speaker and Scientific Writer
Life Science and Lab Water Industries


Laura Bush

Editorial Director

This is a FREE streaming audio Webcast and does not require a phone line. If you have any questions regarding this Webcast, please contact Kristen Moore, kmoore@advanstar.com.

Register for this FREE Webcast!

 If you have previously registered for this event, please login below:

Registration is required to attend this event. Please register now.
First Name*
Last Name*
Job Title*
Organization Name*
Organization Address*
Organization Address 2
State or Province*
Zip/Postal Code*
E-mail address*
Work Phone*
What area of research are you most interested in?*ADME & Toxicity
Cell Structure - Invasion/Migration
Infectious Disease
Lead Discovery (HTS & Lead Optimization)
Outsourced Clinical BioAnalytical Svces
Outsourced Discovery/Preclinical Svces
Stem Cell Research
Which applications/ techniques are you most interested in?*Analytical Sample Prep
Bradford/IR Protein Quantitation
Cell Counting/Viability
Cell Culture - Buffers/Media/Plasticware
Drug Absorption/Diffusion Evaluations
Drug Safety/Testing
Flow Cytometry & Imaging
Live Cell Analysis
Other assays
Protein Purif./Concentration/Depletion
RNA Detection
Small Molecules/Inhibitors
Tissue Isolation/Depletion/Enrichment
Western Blotting
Water Purification
You must have javascript and cookies enabled to complete registration.
Please enable Cookies in your browser before registering for the webcast.
*Denotes required.

Advanstar Communications provides certain customer contact data (such as customers' names, addresses, phone numbers and e-mail addresses) to third parties who wish to promote relevant products, services and other opportunities which may be of interest to you. If you do not want Advanstar Communications to make your contact information available to third parties for marketing purposes, simply call (toll free) 1-866-529-2922 at any time, or fax us at 1-218-740-6417. Outside the U.S., please phone 1-218-740-6395.

Contact us by mail at Advanstar Communications Inc., 131 West First St., Duluth, MN 55802-2065, USA.