The Use of Solid Core Technology in the Pharmaceutical Environment

Recorded on March 25, 2014

Since the introduction of solid core technology, there has been great interest within the separation science field to look at ways in which this innovative technology can be employed in a variety of different industries. One such area is the pharmaceutical arena, where there is a broad range of sample types as well as requirements throughout the process of developing new chemical entities. This presentation will look at how the technology of solid core can be readily adapted to cope with the various challenges associated with the pharmaceutical sector, looking at various sample matrices and various molecular entities, from small molecules to large biomolecules.

The presentation will seek to advise users on appropriate column selection, with an insight into how varying the solid core to porous layer can allow the user to optimize separation performance by reducing extra band broadening. Data will also be presented that demonstrates how this technology is inherently more robust than standard fully porous systems when analyzing biological extracts, routinely used in DMPK departments, resulting in longer column lifetimes.


Laura Bush

Editorial Director


Dafydd Milton

Product Manager, LC & LC-MS Columns
Chromatography Consumables
Thermo Fisher Scientific

Tony Edge
R&D Principal
Chromatography Consumables
Thermo Fisher Scientific

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