Event Date: August 13, 2013 at 8:00 am PDT / 11:00 am EDT / 16:00 BST / 17:00 CEDT

The last decade has witnessed a significant increase in adoption of ion chromatography (IC) in the pharmaceutical industry. This trend is reflected by the increased number of IC-based methods in the United States Pharmacopeia National Formulary (USP-NF). IC methods have been developed for the assay of drug substances and drug products, as well as the determination of related substances and impurities in drug substances and drug products. IC is also commonly used to assay for excipients and active pharmaceutical ingredient (API) counterions. Most IC assays feature an ion-exchange separation followed by suppressed conductivity detection, but there are IC methods in the USP-NF that use other detection techniques. This webinar will review the basics of modern IC, discuss some of the methods found in USP-NF monographs, and detail the development of IC methods for excipients, counterions, related substances, and APIs. Method discussion will highlight why the chosen compounds are well-suited for IC, the choice of separation mode, the choice of detector, and the advantages of the IC method over other possible solutions.


Moderator:

Laura Bush

Editorial Director
LCGC North America

Speaker:

Jeff Rohrer

Director of Applications
Development,
Chromatography Products,
Thermo Fisher Scientific


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