Purification of Monoclonal Antibodies Using Various Modes of Analytical Chromatography
Event Date: September 19, 2012 at 02:00 PM EDT
In recent years, advances in biotechnology have resulted in the increased use of monoclonal antibodies (mAbs) as the main constituent of therapeutic drugs and as diagnostic agents. Because of this increased commercial application, it is important for the bioanalytical chemist to have access to the tools necessary for rapid and simple purification of mAbs. HPLC is a powerful and convenient tool for the analysis of mAbs and their isomers and impurities, including aggregates, oligomers, and mAb fragments. This presentation will discuss the use of HPLC columns from various chromatographic modes for the purification, isolation and analysis of mAbs.


Moderator:

Steve Brown

Technical Editor
LCGC North America

Speakers:

Atis Chakrabarti, Ph.D.

Manager, Technical Service, Laboratory Products
Tosoh Bioscience LLC


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