Tips and Tricks for LC–MS-MS Method Development — Getting Ultimate Performance for Multiresidue Analysis

On Demand Webcast:

This webcast will feature technical speakers from Phenomenex and AB SCIEX discussing the valuable tips and tricks every laboratory scientist or method development chemist should know about optimizing HPLC and mass spectrometry conditions to obtain the most sensitive and robust method possible, particularly for analysis of a broad range of compounds in a single run. Key Learning Objectives:

  • Learn method development techniques to improve multiresidue analysis by LC–MS-MS, with a focus on developing methods to separate and detect compounds that range in polarity, chemical composition, solubility, and stability.
  • Gain a better understanding of how to troubleshoot HPLC methodology, including column stationary phase selection, mobile phase compositional changes, and solvent flow rates, and how those selections can improve peak shape, compound retention, and sensitivity for multianalyte analysis.
  • Learn how to optimize key parameters for mass spectrometry analysis to improve sensitivity, reduce noise, improve number of points per peak, and optimize for analysis that includes a variety of different analytes.


Steve Brown

Technical Editor
LCGC North America


Philip Koerner, Ph.D.

Senior Technical Manager

Paul Winkler, Ph.D.
Senior Field Application Specialist

This is a FREE streaming audio Webcast and does not require a phone line. If you have any questions regarding this Webcast, please contact Jamie Carpenter,

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